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Phone: (727) 597-4787
Regenerative medicine is exploring exciting new techniques to regrow, repair or replace diseased or damaged cells, tissues and organs. This new branch of medicine involves the generation and use of therapeutic stem cells, tissue engineering, and the development of artificial organs.
Regrowing, repairing, or replacing damaged cells is not a new idea, but with constant research, improvements, and extensive clinical studies, the specialism is evolving rapidly.
Recent research led by Carnegie Institution for Science’s Chen-Ming Fan, Ph.D., and published in Nature Cell Biology reveals the existence of tendon stem cells that could potentially be harnessed to improve tendon healing and even to avoid surgery.
“Tendons are the connective tissue that tethers our muscles to our bones,” Dr. Fan explained. “They improve our stability and facilitate the transfer of force that allows us to move. But they are also particularly susceptible to injury and damage.”
The current mechanistic understanding of tendon regeneration is limited but tendon injuries cause prolonged disability and rarely recover completely. The culprit is fibrous scar buildup (scar tissue) which disrupts the tissue structure of the tendon.
This makes recovery from torn rotator cuffs, jumper’s knee and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures, limited mobility and require long-term pain management or even surgery.
Stem cells are the body’s raw material. They are “blank” cells, associated with nearly all tissue types, which have not yet differentiated into a particular functionality. Under the right circumstances, stem cells divide to form more cells. They can self-renew, to produce a pool from which newly differentiated cell types can form to support a specific tissue’s function. For example, muscle stem cells can differentiate into muscle cells. Until now, tendon stem cells were unknown.
“Because tendon injuries rarely heal completely, it was thought that tendon stem cells might not exist,” says developmental cell biologist Tyler Harvey from the Carnegie Institution for Science, who worked alongside Dr. Fan. “Many searched for them to no avail, but our work defined them for the first time.”
“Tendon stem cells exist, but they must outcompete the scar tissue precursors in order to prevent the formation of difficult, fibrous scars,” Dr. Chen-Ming Fan, explained. “Finding a therapeutic way to block the scar-forming cells and enhance the tendon stem cells could be a game-changer when it comes to treating tendon injuries.”
Dr. Susanti Chowdhury is experienced at providing various regenerative medicine treatments, including Regenerative Therapy in Clearwater and St. Petersburg. Regenerative Therapy can be successfully applied in the treatment of injured joints where tissue has been damaged, as Regenerative Therapy promotes the body’s natural healing process. Medical benefits of Regenerative Therapy include minimum pain and discomfort, a very low chance of material rejection and fast recovery after the treatment.
If you’re unsure whether you are a suitable candidate for regenerative medicine treatment in Clearwater and St. Petersburg area, FL, Dr. Chowdhury will evaluate your condition and suggest the most effective treatment. Do not hesitate to contact us with any questions you might have.
The material contained on this site is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE, and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions or concerns you may have regarding your health.
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