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Bradenton, FL 34202
Pinellas Park Location
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Largo, FL 33771
Phone: (727) 597-4787
For many years, scientists have been working on finding ways to control how stem cells develop into other cell types, hoping to create new cures. One step towards success has been made, as pluripotent cells, i.e., stem cells that have the ability to turn into any kind of cell, have been grown by researchers. When placed into a specific space, gene networks are triggered that define the ultimate fate of the cells. Most other medical research on pluripotent stem cells has focused on modifying the combination of growth solutions in which the cells are placed. The discovery that there is a biomechanical element to controlling how stem cells transform into other cell types is an important piece of the puzzle as scientists try to harness stem cells for medical uses.
Researchers have engineered human liver tissue that can be implanted in a mouse’s body. The mouse retains its own liver, which keeps functioning in the traditional way. The added piece, however, metabolizes drugs in the same way humans do. This allows scientists to test sensitivity to toxicity in mice. Using engineered human tissue in this way could cut down on the time and cost of producing new drugs, as well as allow for critical examinations of drug-drug interactions within a human-like system.
Researchers have finished an experiment on growing stem cells from their pluripotent state into a mature bone graft, which can potentially be transplanted into the human body. Previously, scientists had only developed the cells to a primitive version of the tissue, which was not fully functional. Additionally, the study showed that when implanted in immunodeficient mice, the bone does not grow abnormally, which is common after implanting stem cells or bone scaffolds alone.
Read more about scientific findings in our regenerative medicine Tampa blog
Until now, cartilage has been very difficult, if not impossible, to repair due to the fact that it lacks a blood supply to trigger regeneration. Microfracture surgeries have been around 50% successful in treating injuries in young adults, and not at all successful in patients with widespread cartilage damage arising from conditions like osteoarthritis.
Tissue engineers have developed a biological gel that can be injected into a zone with cartilage defects. This can be followed by microfracture surgery to create an environment that facilitates regeneration. In order for this gel to stay in place within the knee, researchers also developed a new biological adhesive that is able to connect to both the gel as well as the damaged cartilage in the knee, keeping the newly regenerated cartilage in place.
In a recent study, 15 patients who used the gel/adhesive combo followed by surgery have reported decreased pain at six months post-surgery. In contrast, the majority of microfracture patients, after an initial decrease in pain, returned to their original pain level within six months.
Find out more about how regenerative medicine in Largo, Tampa, Clearwater, Pinellas Park, cellular therapies, and Regenerative Therapy can be the best treatment method for your condition and the best prevention for future traumas. Visit our website or call our friendly staff today at (727) 597-4787.
The material contained on this site is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE, and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions or concerns you may have regarding your health.
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